New York City's ___ Place

ASTOR

This historic NYC location shares its name with a prominent family in American history.

The clue "New York City's ___ Place" refers to Astor Place, a well-known public square in Manhattan named after John Jacob Astor, a prominent 19th-century businessman. The answer "ASTOR" fits because it completes the name of this historic location, which is famous for its cultural significance and the iconic Astor Place Cube sculpture. If you're familiar with NYC landmarks, this one should be straightforward.