Like easy-to-get meds, in brief

OTC

Think of the aisle where you’d grab pain relievers without a prescription.

The clue hints at medications you can buy without a prescription, which are often called "over-the-counter" drugs. "In brief" signals that the answer is an abbreviation, so "over-the-counter" gets shortened to "OTC." It’s a straightforward definition with a common medical shorthand many people recognize.