Way to begin gaming, say

PRESSSTART

Think of the two words you might see on a retro console screen before playing.

This clue plays on the phrase "press start," which is the literal action you take to begin a video game. The word "gaming" hints at video games, while "way to begin" suggests the first step—pressing the Start button. "Say" signals that the answer is a common expression, not a literal instruction, so the answer is written as one word: PRESSSTART.