20 Down

NYT Daily • September 5, 2025

Constriction of the pupils

Answer:

MIOSIS

Hint:

Think of the opposite of dilation in the eyes, often caused by bright light or certain medications. This term is derived from Greek, meaning "to close.

Explanation:

Constriction of the pupils" directly refers to miosis, the medical term for when the pupils shrink or narrow, often in response to bright light or certain drugs. The clue is straightforward with no wordplay—it’s a direct definition, so you just need to recall the scientific term for this eye reaction. If you’ve heard of mydriasis (pupil dilation), miosis is the opposite process.

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