Make annoyed

ROIL

Think of stirring up trouble in a liquid—or someone’s emotions—until things feel unsettled.

Make annoyed" hints at a word meaning to upset or disturb someone, and "roil" fits perfectly—it means to irritate or agitate, like stirring up trouble. The word can also describe water being churned up, which ties into the idea of causing unrest. It’s a concise verb that matches the clue’s straightforward definition without any hidden wordplay.