Microdosing substance

LSD

This psychedelic compound, first synthesized in 1938, is often associated with tiny doses for cognitive enhancement rather than full hallucinogenic effects.

"Microdosing substance" hints at a drug often taken in very small amounts for subtle effects, and LSD is a well-known psychedelic commonly used this way. The clue plays on the modern trend of microdosing—taking tiny doses of hallucinogens like LSD to boost creativity or focus without full tripping. It’s a straightforward reference since LSD is one of the most famous substances associated with this practice.