Tick-borne affliction, informally

Answer:

LYME

Hint:

This bacterial infection often starts with a bullseye-shaped rash and is named after a Connecticut town where it was first identified.

Explanation:

This clue hints at a disease spread by ticks, using "informally" to signal a casual or shortened name. "Lyme" refers to Lyme disease, a bacterial infection transmitted through tick bites, often associated with symptoms like rash and fatigue. The wordplay is straightforward—no tricks—just a common nickname for the condition.

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General solving tip

When a clue says 'informally,' 'slangily,' or 'casually,' think slang, clipped forms, or texting abbreviations. Try the short casual word you'd use in speech or a message.

More tips → General Hints