17 Across

NYT Daily ? September 12, 2025

Receiving a certain hormone treatment

Answer:

ONESTROGEN

Hint:

Think of a phrase that sounds like a popular supplement but actually describes undergoing therapy with a key female hormone.

Explanation:

The clue plays on the phrase "on estrogen," which describes someone undergoing estrogen hormone therapy. The word "receiving" hints at the prefix "on" (as in "on medication"), while "a certain hormone treatment" directly points to "estrogen." Together, they form "ONESTROGEN," blending the idea of being on the hormone with its name.

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General solving tip

Match the clue's grammar: plural with plural, past with past. If the clue ends in 's' or uses a past-tense verb, mirror that form in the entry.

More tips → General Hints