Catholic university in Florida or its home town

STLEO

This school near Tampa was founded by Benedictine monks and shares its name with a 6th-century pope known for his charity.

This clue points to "STLEO," which is short for Saint Leo University, a well-known Catholic university in Florida. The answer also doubles as the name of its home town, Saint Leo, cleverly combining both parts of the clue into one abbreviation. The wordplay relies on the shared initials, making "STLEO" fit neatly for both the school and its location.