Public health agcy.

Answer:

CDC

Hint:

This U.S. organization monitors disease outbreaks and sets vaccination guidelines, often in the news during pandemics. Its initials stand for "Centers for...".

Explanation:

"Public health agcy." is a straightforward abbreviation clue where "agcy." stands for "agency." The answer is "CDC," which is the widely recognized shorthand for the Centers for Disease Control and Prevention, the U.S. government’s main public health organization. The clue relies on common knowledge of the acronym rather than wordplay or tricks.

More Clues from This Puzzle

15 Down

5 letters

Make a big step, perhaps

25 Across

4 letters

Pro ___

32 Across

9 letters

Kicked off, as a business

51 Across

3 letters

Small square

General solving tip

Quoted clues often indicate a spoken phrase, interjection, or a title. Think of something you'd say out loud or see as a headline.

More tips → General Hints