Remove surgically, as tissue

ABLATE

Think of a medical procedure that uses heat, cold, or lasers to destroy unwanted cells, often in treating tumors or arrhythmias. The word starts with "A" and sounds like "uh-BLAYT."

The clue "Remove surgically, as tissue" points to "ABLATE," a medical term meaning to cut away or destroy tissue, often with lasers or other precise methods. It’s a straightforward definition with no wordplay—just a direct reference to a surgical procedure. If you’ve heard of "ablation" in medical contexts, this is the verb form of that same idea.