Woman's name that's the first three letters of 46-Across

EVA

Think of the biblical figure often associated with the first woman, whose name fits neatly into this three-letter space.

This clue points to a woman’s name that matches the first three letters of the answer to 46-Across. Since the answer is "EVA," it means 46-Across must start with "EVA," like "EVACUATE" or "EVALUATE." The trick is solving 46-Across first to confirm, but the clue itself is straightforward—just a name hidden in plain sight.