"Are you done guessing?"

GIVEUP

This phrase might be what you say when you're out of ideas during a challenging game or puzzle. Think of surrendering in a playful way.

The clue "Are you done guessing?" hints at the phrase someone might say when they're frustrated and ready to quit trying. "Give up" is a common response in that situation, and the answer is written as one word, GIVEUP, to fit crossword style. The wordplay is straightforward—it’s a direct question implying surrender, with the answer being the literal action of giving up.