Sarcastic question answered by the starts of 17-, 25-, 51- and 59-Across

Answer:

SO, WHAT ELSE IS NEW?

Hint:

Not available

Explanation:

This clue is a meta-reference where the answer is a snarky phrase built from the first letters of four other Across clues. The starts of 17-, 25-, 51-, and 59-Across spell out "S," "W," "E," and "N," which stand for the words in "SO, WHAT ELSE IS NEW?"—a classic sarcastic remark implying nothing is surprising. The humor comes from the answer itself being a dismissive question, fitting the tone of the clue.

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